Genital Warts: Topical BCG Works Well: In a 6-month DB PC study of 50 patients with genital warts (condylomata acuminata), topical application of viable bacille Calmette-Guerin (BCG) weekly for 6 consecutive weeks, and, if need, another intensive three-times-a-week course for 3 consecutive weeks was given. Disappearance of all condylomata acuminata was achieved in 20 (80%) of the 25 patients after a maximum of six BCG applications. Three patients (12%) needed another, more extensive, course, resulting in complete clearance 3 weeks later. Only 2 patients (8%) did not achieve a full response. No response was detected in the placebo group. Minimal side effects, such as transient erythema and fever, were recorded. No recurrence during follow-up. Application of viable bacille Calmette-Guerin topically as a potential therapeutic modality in condylomata acuminata: a placebo-controlled study. Metawea B, El-Nashar AR, et al. Cairo University Hospital, Egypt. Urology. 2005 Feb;65(2):247-50

Warts: Salicylic Acid, ?Castor Oil, ??Cimetidine: Plantar warts most commonly come viruses picked up on feet from swimming pools and shared swimming pool showers. One study found 1.2% of gym players using locker room but not showering had warts vs. 27% using same locker room and showering. Salicylic acid is the most common treatment.  Adding cryosurg after 3 months was no added benefit in one large random study. Nothing else found of benefit in research although one physician assistant on line recommends castor oil BID with compresses for when salicylic not effective or tolerated. Several studies with cimetidine with 2 DB not finding benefit but third finding marginal benefit. BMJ on 8/31/02 says cryotherapy no advantage and salicylic acid still best.  Cryotherapy is quite expensive and favored by some dermatologists.

Warts: Duct Tape Better than Cryotherapy: 51 of 61 children ages 3-21 completed study comparing duct tape to nitrogen treatment. 85% duct tape vs. 60% nitrogen cured within 2 months. Duct tape put on Q6days, then soak in water, file with emery board or pumice stone, reapply next morning. Tape thought to irritate wart and stimulate immune system. A Chicago pediatric dermatologist combines salicyclic acid QHS with duct tape. 10/02 Arch Pediatric & Adol. (Ed: My children picked up plantars warts at the pool and generic salicylic acid and duct tape worked for both.)